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Article

The GlpF residue Trp219 is part of an amino-acid cluster crucial for aquaglyceroporin oligomerization and function.

Biochimica et biophysica acta. Biomembranes - 1 Apr 2018

Trefz Margareta, Keller Rebecca, Vogt Miriam, Schneider Dirk

Abstract excerpt

The vestibule loop regions of aquaglyceroporins are involved in accumulation of glycerol inside the channel pore. Even though most loop regions do not show high sequence similarity among aquaglyceroporins, loop E is highly conserved in aquaglyceroporins, but not in members of the homologous aquaporins. Specifically, a tryptophan residue is extremely conserved within this loop. We have investigated the role of...

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Identifiers

PMID: 29069569
DOI: 10.1016/j.bbamem.2017.10.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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