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Article

Modulation of extracytoplasmic function (ECF) sigma factor promoter selectivity by spacer region sequence.

Nucleic acids research - 9 Jan 2018

Gaballa Ahmed, Guariglia-Oropeza Veronica, Dürr Franziska, Butcher Bronwyn G, Chen Albert Y, Chandrangsu Pete, Helmann John D

Abstract excerpt

The ability of bacteria to adapt to stress depends on the conditional expression of specific sets of genes. Bacillus subtilis encodes seven extracytoplasmic function (ECF) sigma (σ) factors that regulate functions important for survival under conditions eliciting cell envelope stress. Of these, four have been studied in detail: σM, σW, σX and σV. These four σ factors recognize overlapping sets of promoters,...

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Identifiers

PMID: 29069433
DOI: 10.1093/nar/gkx953
PMCID: PMC5758882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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