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Article

The Extracytoplasmic Function Sigma Factor σ S Protects against both Intracellular and Extracytoplasmic Stresses in Staphylococcus aureus

9 Jun 2012

Abstract excerpt

Previously we identified a novel component of the Staphylococcus aureus regulatory network, an extracytoplasmic function σ-factor, σ(S), involved in stress response and disease causation. Here we present additional characterization of σ(S), demonstrating a role for it in protection against DNA damage, cell wall disruption, and interaction with components of the innate immune system. Promoter mapping reveals the...

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PMID: 22685284
DOI: 10.1128/jb.00484-12

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