Article
Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors.
Journal of bacteriology - 1 Oct 2007
Mascher Thorsten, Hachmann Anna-Barbara, Helmann John D
Abstract excerpt
Bacillus subtilis encodes seven extracytoplasmic function (ECF) sigma factors that regulate partially overlapping regulons related to cell envelope homeostasis and antibiotic resistance. Here, we investigated their physiological role by constructing a mutant set of single, double, triple, and quadruple ECF sigma factor deletions in the undomesticated B. subtilis strain NCIB3610. This mutant set was subsequently...
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