Article
The extracytoplasmic function sigma factor EcfO protects Bacteroides fragilis against oxidative stress.
Journal of bacteriology - 1 Jan 2013
Ndamukong Ivan C, Gee Jason, Smith C Jeffrey
Abstract excerpt
The anaerobe Bacteroides fragilis is a highly aerotolerant, opportunistic pathogen that is an important component of the human intestinal microbiota. Aerotolerance has been linked to a robust oxidative stress response, which in turn is necessary for maximal virulence in a mouse intra-abdominal abscess model. During oxidative stress, there is a dynamic change in gene expression that encompasses a third of the...
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