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Article

Interferon regulatory factor 6 variants affect nasolabial morphology in East Asian populations.

Archives of oral biology - 1 Jan 2018

Tomita Daisuke, Yamaguchi Tetsutaro, Nakawaki Takatoshi, Hikita Yu, Adel Mohamed, Kim Yong-Il, Haga Shugo, Takahashi Masahiro, Kawaguchi Akira, Isa Mutsumi, Park Soo-Byung, Ishida Hajime, Maki Koutaro, Kimura Ryosuke

Abstract excerpt

OBJECTIVE: The interferon regulatory factor 6 gene (IRF6) is one of the most conspicuous genes among a large number of candidate risk genes for non-syndromic cleft lip with or without cleft palate, which is considered to be a multifactorial defect. Variants of IRF6 are also suggested to affect normal craniofacial variations, especially in the area of the nose and the upper lip. In the present study, we used...

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Identifiers

PMID: 29065370
DOI: 10.1016/j.archoralbio.2017.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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