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Article

[Clinical significance and mechanism of upregulation of PI3Kp110α in non-small cell lung carcinoma].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 23 Oct 2017

Xiong Y, Qu L L, Li D, Wang Y, Li T

Abstract excerpt

Objective: To investigate the clinical significance and mechanism of upregulation of phosphoinositide 3-kinase p110α(PI3Kp110α)in non-small cell lung carcinoma (NSCLC). Methods: Expressions of PI3Kp110α and other components in PI3K signaling pathway (including phospho-Akt (p-Akt, Ser 473), MET, ROS1, HER-2, ALK, total EGFR and mutant EGFR) and p53 (the transcription factor of PIK3CA) mutation in NSCLC were...

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Source

Identifiers

PMID: 29061016
DOI: 10.3760/cma.j.issn.0253-3766.2017.10.004

Genes

EGFR
MET
ALK
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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