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Article

DGRPool, a web tool leveraging harmonized Drosophila Genetic Reference Panel phenotyping data for the study of complex traits.

eLife - 21 Oct 2024

Gardeux Vincent, Bevers Roel P J, David Fabrice P A, Rosschaert Emily, Rochepeau Romain, Deplancke Bart

Abstract excerpt

Genome-wide association studies have advanced our understanding of complex traits, but studying how a GWAS variant can affect a specific trait in the human population remains challenging due to environmental variability. Drosophila melanogaster is in this regard an excellent model organism for studying the relationship between genetic and phenotypic variation due to its simple handling, standardized growth...

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PMID: 39431984
DOI: 10.7554/eLife.88981
PMCID: PMC11493408

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