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Article

A new epitope-tagged Pkhd1 allele sheds light on fibrocystin signaling.

Kidney international - 1 Nov 2017

Lea Wendy A, Ward Christopher J

Abstract excerpt

In this issue of Kidney International, Outeda et al. present a new epitope-tagged allele of murine Pkhd1 that allows the monitoring of functional fibrocystin in vivo from the extreme C-terminus of the molecule. This work also shows that the removal of two-thirds of the intracellular tail of fibrocystin does not result in cystogenesis in either the liver or kidney, with major implications for our understanding of...

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Identifiers

PMID: 29055424
DOI: 10.1016/j.kint.2017.05.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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