Article
Determination of Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Reverse Transcriptase Multiplex Ligation-Dependent Probe Amplification Classifier: A CALYM Study.
The Journal of molecular diagnostics : JMD - 1 Nov 2017
Bobée Victor, Ruminy Philippe, Marchand Vinciane, Viailly Pierre-Julien, Abdel Sater Ahmad, Veresezan Liana, Drieux Fanny, Bérard Caroline, Bohers Elodie, Mareschal Sylvain, Dubois Sydney, Jais Jean-Philippe, Leroy Karen, Figeac Martin, Picquenot Jean-Michel, Molina Thierry Jo, Salles Gilles, Haioun Corinne, Tilly Hervé, Jardin Fabrice
Abstract excerpt
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma. It includes three major subtypes termed germinal center B-cell-like, activated B-cell-like, and primary mediastinal B-cell lymphoma. With the emergence of novel targeted therapies, accurate methods capable of interrogating this cell-of-origin classification should soon become essential in the clinics. To address this issue, we...
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