Article
A novel next generation sequencing assay as an alternative to currently available methods for hepatitis C virus genotyping.
Journal of virological methods - 1 Jan 2018
Dirani G, Paesini E, Mascetra E, Farabegoli P, Dalmo B, Bartolini B, Garbuglia A R, Capobianchi M R, Sambri V
Abstract excerpt
Chronic HCV infection is one of the leading causes of liver-related death and in many countries it is a primary reason for having a liver transplant. HCV genotype identification has long been used in the clinical practice, since different genotypes have different response rates and required different doses and durations of IFN/RBV treatment; moreover both the frequency and the pattern of resistance to different...
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