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Article

Colorectal carcinoma tumour budding and podia formation in the xenograft microenvironment.

PloS one - 1 Jan 2017

Prall Friedrich, Maletzki Claudia, Hühns Maja, Krohn Mathias, Linnebacher Michael

Abstract excerpt

Tumour budding and podia formation are well-appreciated in surgical pathology as an aggressive invasion phenotype of colorectal carcinoma cells that is attained in the microenvironment of the invasive margin. In this study, we addressed how tumour budding and podia formation feature in xenografts. Primary colorectal carcinomas (N = 44) of various molecular types (sporadic standard type, high-degree...

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Identifiers

PMID: 29040282
DOI: 10.1371/journal.pone.0186271
PMCID: PMC5645095

Genes

SMAD4

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