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Article

The impact of CpG island methylator phenotype and microsatellite instability on tumour budding in colorectal cancer.

Histopathology - 1 Nov 2012

Zlobec Inti, Bihl Michel P, Foerster Anja, Rufle Alex, Lugli Alessandro

Abstract excerpt

AIMS: In colorectal cancer, tumour budding, a process likened to epithelial mesenchymal transition, is an adverse prognostic factor which is rarely found in tumours with high-level microsatellite instability (MSI-H). Cases with MSI-H or high-level CpG island methylator phenotype (CIMP-H) have sim...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22803799
DOI: 10.1111/j.1365-2559.2012.04273.x

Genes

BRAF
KRAS
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22803799-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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