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Systematic review of tumour budding and association with common mutations in patients with colorectal cancer.

Critical reviews in oncology/hematology - 1 Nov 2021

Hatthakarnkul Phimmada, Quinn Jean A, Matly Amna Ahmed Mohemmd, Ammar Aula, van Wyk Hester C, McMillan Donald C, Edwards Joanne

Abstract excerpt

INTRODUCTION: Despite a well-known prognostic role in colorectal cancer, the genomic profiling of tumour budding remains to be elucidated. We aim to review the association of common mutations with tumour budding. METHODS: A systematic review of studies relating to tumour budding and genetic mutation in CRC was performed. The relationship between mutational status and tumour budding was evaluated using...

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PMID: 34619332
DOI: 10.1016/j.critrevonc.2021.103490

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