Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor budding at the invasive front of colorectal cancer may not be associated with the epithelial-mesenchymal transition.

Human pathology - 1 Feb 2017

Yamada Noriyuki, Sugai Tamotsu, Eizuka Makoto, Tsuchida Koudai, Sugimoto Ryo, Mue Yoshiharu, Suzuki Masamichi, Osakabe Mitsumasa, Uesugi Noriyuki, Ishida Kazuyuki, Otsuka Kouki, Matsumoto Takayuki

Abstract excerpt

Tumor budding is thought to reflect the epithelial-mesenchymal transition (EMT). However, the molecular mechanism linking tumor buds and the EMT remains unclear. Here, we examined the induction of tumor budding and EMT and their association with EMT-related proteins (ZEB1, TWIST, SNAIL, and SLUG) in colorectal cancer (CRC). Immunohistochemical expression of pan-cytokeratin was examined for identification of tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epithelial-Mesenchymal Transition
Share to Keratins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Grading

Share to Snail Family Transcription Factors

Share to Stromal Cells

Share to Tissue Array Analysis

Share to Twist-Related Protein 1

Share to Zinc Finger E-box-Binding Homeobox 1

Source

Identifiers

PMID: 27836787
DOI: 10.1016/j.humpath.2016.10.007

Genes

ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor budding at the invasive front of colorectal cancer may not be associated with the epithelial-mesenchymal transition.PMID 27836787Read ↗

Tumor budding in colorectal carcinoma assessed by cytokeratin immunostaining and budding areas: Possible involvement of c‐MetSemantic proximity Read ↗

Tumor Budding: The Name is EMT. Partial EMT.Semantic proximity Read ↗

RAS, Cellular Plasticity, and Tumor Budding in Colorectal CancerSemantic proximity Read ↗

Tumor Budding in Colorectal Carcinoma: Confirmation of Prognostic Significance and Histologic Cutoff in a Population-based Cohort.Semantic proximity Read ↗

Systematic review and meta-analysis of the impact of tumour budding in colorectal cancer.Semantic proximity Read ↗

Establish a novel tumor budding-related signature to predict prognosis and guide clinical therapy in colorectal cancerSemantic proximity Read ↗

Establish a novel tumor budding-related signature to predict prognosis and guide clinical therapy in colorectal cancerSemantic proximity Read ↗

Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching.Semantic proximity Read ↗

TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancerSemantic proximity Read ↗

Systematic review of tumour budding and association with common mutations in patients with colorectal cancer.Semantic proximity Read ↗

Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer.Semantic proximity Read ↗

Prognostic impact of tumor budding in endometrial carcinoma within distinct molecular subgroups.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.