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Article

Blunted basal corticosterone pulsatility predicts post-exposure susceptibility to PTSD phenotype in rats.

Psychoneuroendocrinology - 1 Jan 2018

Danan Dor, Matar Michael A, Kaplan Zeev, Zohar Joseph, Cohen Hagit

Abstract excerpt

The basal activity of the hypothalamic-pituitary-adrenal axis is highly dynamic and is characterized by both circadian and ultradian (pulsatile) patterns of hormone secretion. Pulsatility of glucocorticoids has been determined to be critical for optimal transcriptional, neuroendocrine, and behavioral responses. We used an animal model of post-traumatic stress disorder (PTSD) to assess whether stress-induced...

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Identifiers

PMID: 29035710
DOI: 10.1016/j.psyneuen.2017.09.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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