Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association analysis of the ACTN3 R577X polymorphism with passive muscle stiffness and muscle strain injury.

Scandinavian journal of medicine & science in sports - 1 Mar 2018

Miyamoto N, Miyamoto-Mikami E, Hirata K, Kimura N, Fuku N

Abstract excerpt

Passive muscle stiffness is considered to be a major factor affecting joint flexibility and is thought to relate to the occurrence of muscle strain injury. In skinned muscle fiber experiments, the R577X polymorphism of the α-actinin-3 gene (ACTN3) has been associated with passive muscle stiffness. Our primary purpose was to clarify whether the ACTN3 R577X polymorphism influences passive stiffness of human muscle...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actinin
Share to Elastic Modulus
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterozygote

Share to Muscle Fibers, Fast-Twitch

Share to Polymorphism, Genetic

Share to Young Adult

Source

Identifiers

PMID: 29032593
DOI: 10.1111/sms.12994

Genes

ACTN3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association analysis of the ACTN3 R577X polymorphism with passive muscle stiffness and muscle strain injury.PMID 29032593Read ↗

The association between the ACTN3 R577X polymorphism and noncontact acute ankle sprains.Semantic proximity Read ↗

ACTN3 R577X Polymorphism Is Associated With the Incidence and Severity of Injuries in Professional Football Players.Semantic proximity Read ↗

Association between ACTN3 R577X genotype and risk of non-contact injury in trained athletes: A systematic review.Semantic proximity Read ↗

Alpha-Actinin-3 Deficiency Might Affect Recovery from Non-Contact Muscle Injuries: Preliminary Findings in a Top-Level Soccer Team.Semantic proximity Read ↗

Effect of ACTN3 R577X Genotype on Injury Epidemiology in Elite Endurance Runners.Semantic proximity Read ↗

Human alpha-actinin-3 genotype association with exercise-induced muscle damage and the repeated-bout effect.Semantic proximity Read ↗

COL5A1 rs12722 polymorphism is not associated with passive muscle stiffness and sports-related muscle injury in Japanese athletes.Semantic proximity Read ↗

ESR1 rs2234693 Polymorphism Is Associated with Muscle Injury and Muscle Stiffness.Semantic proximity Read ↗

ACTN3 c.1729C>T Polymorphism Might Not Be a Standalone Factor in Non-contact Musculoskeletal Injury: A Systematic Review and Meta-analysis.Semantic proximity Read ↗

History-dependent force, angular velocity and muscular endurance in ACTN3 genotypes.Semantic proximity Read ↗

Simple Method to Genotype the ACTN3 r577x Polymorphism.Semantic proximity Read ↗

Effects of the ACTN3 R577X Genotype on the Muscular Strength and Range of Motion Before and After Eccentric Contractions of the Elbow Flexors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.