Effect of ACTN3 R577X Genotype on Injury Epidemiology in Elite Endurance Runners.

doi:10.3390/genes12010076

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Article

Effect of ACTN3 R577X Genotype on Injury Epidemiology in Elite Endurance Runners.

Genes - 8 Jan 2021

Gutiérrez-Hellín Jorge, Baltazar-Martins Gabriel, Aguilar-Navarro Millán, Ruiz-Moreno Carlos, Oliván Jesús, Del Coso Juan

Abstract excerpt

The p.R577X polymorphism (rs1815739) in the ACTN3 gene causes individuals with the ACTN3 XX genotype to be deficient in functional α-actinin-3. Previous investigations have found that XX athletes are more prone to suffer non-contact muscle injuries. This investigation aimed to determine the influence of the ACTN3 R577X polymorphism in the injury epidemiology of elite endurance athletes. Using a cross-sectional...

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PMID: 33430120
DOI: 10.3390/genes12010076
PMCID: PMC7828078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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