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Article

ACTN3 c.1729C>T Polymorphism Might Not Be a Standalone Factor in Non-contact Musculoskeletal Injury: A Systematic Review and Meta-analysis.

Sports medicine (Auckland, N.Z.) - 1 Mar 2026

Varillas-Delgado David, Villaoslada Estela, Clavaín Laura

Abstract excerpt

BACKGROUND: To date, multiple studies have presented the association of the c.1729C>T polymorphism in the ACTN3 gene with non-contact musculoskeletal injuries, but there are discrepancies and a lack of consensus in this area of research. OBJECTIVE: The aim of this systematic review and meta-analysis was to determine the influence of genotypes and alleles in the c.1729C>T polymorphism of the ACTN3 gene on the...

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Actinin
Alleles
ACTN3 gene
Genotype
Incidence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 41296289
DOI: 10.1007/s40279-025-02368-2

Genes

ACTN3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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