Article
Generation and multi-phenotypic high-content screening of Coxiella burnetii transposon mutants.
Journal of visualized experiments : JoVE - 13 May 2015
Martinez Eric, Cantet Franck, Bonazzi Matteo
Abstract excerpt
Invasion and colonization of host cells by bacterial pathogens depend on the activity of a large number of prokaryotic proteins, defined as virulence factors, which can subvert and manipulate key host functions. The study of host/pathogen interactions is therefore extremely important to understand bacterial infections and develop alternative strategies to counter infectious diseases. This approach however,...
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