Article
The HACD4 haplotype as a risk factor for atherosclerosis in males.
Gene - 30 Jan 2018
Zivotić Ivan, Djurić Tamara, Stanković Aleksandra, Ivančević Ilija, Končar Igor, Milasinovic Dejan, Stankovic Goran, Alavantić Dragan, Zivković Maja
Abstract excerpt
The 9p21.3 region is rich in regulatory elements and the variants in this region had been robustly associated with carotid plaque (CP) and coronary artery disease (CAD). Recently, the HACD4 was detected as one of the six 9p21.3 differentially expressed genes associated with accelerated atherosclerosis and greater mean lesion area in the Athsq1 congenic mice. We aimed to investigate association of two potentially...
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