Article
1H, 13C and 15N backbone resonance assignments of the β-lactamase BlaP from Bacillus licheniformis 749/C and two mutational variants.
Biomolecular NMR assignments - 1 Apr 2018
Thorn David, Kay Jennifer, Rhazi Noureddine, Dumoulin Mireille, Corazza Alessandra, Damblon Christian
Abstract excerpt
Class A β-lactamases have been widely used as versatile scaffolds to create hybrid (or chimeric) proteins for a series of applications ranging from basic research to medicine. We have, in particular, used the β-lactamase BlaP from Bacillus licheniformis 749/C (BlaP) as a protein scaffold to create model polyglutamine (polyQ) proteins in order to better understand the mechanism(s) by which an expanded polyQ...
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