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Article

The Dopamine D2 Receptor Contributes to the Spheroid Formation Behavior of U87 Glioblastoma Cells.

Pharmacology - 1 Jan 2020

Weissenrieder Jillian S, Reed Jessie L, Green Michelle V, Moldovan George-Lucian, Koubek Emily J, Neighbors Jeffrey D, Hohl Raymond J

Abstract excerpt

BACKGROUND: Glioblastoma multiforme (GBM) is a common and lethal cancer of the central nervous system. This cancer is difficult to treat because most anticancer therapeutics do not readily penetrate into the brain due to the tight control at the cerebrovascular barrier. Numerous studies have suggested that dopamine D2 receptor (D2R) antagonists, such as first generation antipsychotics, may have anticancer...

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Identifiers

PMID: 31645049
DOI: 10.1159/000502562
PMCID: PMC10777736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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