Article

Alcohol Promotes Hepatocellular Carcinoma Metastasis Through SIRT7-Dependent EMT Regulation

2021-11-10

Abstract excerpt

<title>Abstract</title> <p>Background Long-term alcohol use is a confirmed risk factor of liver cancer tumorigenesis and metastasis. Multiple mechanisms responsible for alcohol related tumorigenesis have been proposed, including toxic reactive metabolite production, oxidative stress and fat accumulation which trigger hepatocyte cell death and inflammation. However, mechanisms underlying alcohol-mediated liver ca...

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Literature Corpus work: 711958b3-be13-5f5c-bbdf-da05064a3cf1
DOI: 10.21203/rs.3.rs-983099/v1

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