Article

MicroRNA-744-5p Suppresses Tumorigenesis and Metastasis of Osteosarcoma Through the MAPK/ERK Signaling Pathway by Targeting TGFB1

2021-06-01

Abstract excerpt

<title>Abstract</title> <bold>Background:</bold> Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents, and accumulating evidence has revealed that microRNAs (miRNAs) exert a crucial part in the progression of OS. <bold>Methods: </bold>GSE65071 from the GEO database was analyzed and miR-744-5p was found to be the lowest expressed miRNA. Real-time quantitative PCR (qRT-PCR), West...

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Literature Corpus work: 5a705746-daa3-5054-aeab-7dba5c6ea1bc
DOI: 10.21203/rs.3.rs-545532/v1

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