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Article

Dual Roles of Glutathione in Ecdysone Biosynthesis and Antioxidant Function During Larval Development in Drosophila.

Genetics - 1 Dec 2017

Enya Sora, Yamamoto Chikana, Mizuno Hajime, Esaki Tsuyoshi, Lin Hsin-Kuang, Iga Masatoshi, Morohashi Kana, Hirano Yota, Kataoka Hiroshi, Masujima Tsutomu, Shimada-Niwa Yuko, Niwa Ryusuke

Abstract excerpt

Ecdysteroids, including the biologically active hormone 20-hydroxyecdysone (20E), play essential roles in controlling many developmental and physiological events in insects. Ecdysteroid biosynthesis is achieved by a series of specialized enzymes encoded by the Halloween genes. Recently, a new class of Halloween gene, noppera-bo (nobo), encoding a glutathione S-transferase (GST) in dipteran and lepidopteran...

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Identifiers

PMID: 29021278
DOI: 10.1534/genetics.117.300391
PMCID: PMC5714463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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