Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Susceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: Phenotypic and genotypic insights.

PloS one - 1 Jan 2017

Marmiroli Paola, Riva Beatrice, Pozzi Eleonora, Ballarini Elisa, Lim Dmitry, Chiorazzi Alessia, Meregalli Cristina, Distasi Carla, Renn Cynthia L, Semperboni Sara, Morosi Lavinia, Ruffinatti Federico A, Zucchetti Massimo, Dorsey Susan G, Cavaletti Guido, Genazzani Armando, Carozzi Valentina A

Abstract excerpt

Peripheral neurotoxicity is one of the most distressing side effects of oxaliplatin therapy for cancer. Indeed, most patients that received oxaliplatin experience acute and/or chronic severe sensory peripheral neuropathy. However, despite similar co-morbidities, cancer stage, demographics and treatment schedule, patients develop oxaliplatin-induced peripheral neurotoxicity with remarkably different severity. This...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ganglia, Spinal
Share to Neural Conduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuralgia

Share to Neurotoxicity Syndromes

Share to Organoplatinum Compounds

Share to Oxaliplatin

Share to Peripheral Nervous System

Share to Sciatic Nerve

Source

Open in PubMed Open full text

Identifiers

PMID: 29020118
DOI: 10.1371/journal.pone.0186250
PMCID: PMC5636145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Susceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: Phenotypic and genotypic insights.PMID 29020118Read ↗

Targeting strategies for oxaliplatin-induced peripheral neuropathy: clinical syndrome, molecular basis, and drug development.Semantic proximity Read ↗

Updates on Oxaliplatin-Induced Peripheral Neurotoxicity (OXAIPN)Semantic proximity Read ↗

Oxaliplatin-Induced Neuropathy: Genetic and Epigenetic Profile to Better Understand How to Ameliorate This Side EffectSemantic proximity Read ↗

Probing the peripheral immune response in mouse models of oxaliplatin-induced peripheral neuropathy highlights their limited translatabilitySemantic proximity Read ↗

Vascular dysfunction is at the onset of oxaliplatin-induced peripheral neuropathy symptoms in miceSemantic proximity Read ↗

Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy.Semantic proximity Read ↗

A novel model of paclitaxel-induced peripheral neuropathy produces a clinically relevant phenotype in miceSemantic proximity Read ↗

Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditionsSemantic proximity Read ↗

Genetic polymorphisms in cyclin H gene are associated with oxaliplatin-induced acute peripheral neuropathy in South Indian digestive tract cancer patients.Semantic proximity Read ↗

Development and Validation of the Chemotherapy-induced Peripheral Neuropathy Integrated Assessment – Oxaliplatin Subscale: A Prospective Cohort StudySemantic proximity Read ↗

Associations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 genesSemantic proximity Read ↗

Mechanistic insights into the pathogenesis of microtubule-targeting agent-induced peripheral neuropathy from pharmacogenetic and functional studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.