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Article

Behçet's disease risk association fine-mapped on the IL23R-IL12RB2 intergenic region in Koreans.

Arthritis research & therapy - 10 Oct 2017

Kang Eun Ha, Kim Sewon, Park Min Young, Choi Ji Yong, Choi In Ah, Kim Min Jung, Ha You-Jung, Lee Eun Young, Lee Yun Jong, Lee Eun Bong, Kang Changwon, Song Yeong Wook

Abstract excerpt

BACKGROUND: Behçet's disease (BD) susceptibility had been associated with single-nucleotide polymorphisms (SNPs) in IL23R-IL12RB2, IL10, STAT4, or ERAP1 locus in Japanese, Turkish, Chinese, and other populations, but not in a Korean genome-wide association study (GWAS). We aimed to fine-map BD risk association of these four loci using extensive imputation and additional genotyping for replication. METHODS: In the...

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Identifiers

PMID: 29017598
DOI: 10.1186/s13075-017-1435-5
PMCID: PMC5633897

Genes

ERAP1
ERAP2
STAT4

Provenance

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