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Article

CXCL12-CXCR4 signalling plays an essential role in proper patterning of aortic arch and pulmonary arteries.

Cardiovascular research - 1 Nov 2017

Kim Bo-Gyeong, Kim Yong Hwan, Stanley Edward L, Garrido-Martin Eva M, Lee Young Jae, Oh S Paul

Abstract excerpt

AIMS: Chemokine CXCL12 (stromal derived factor 1: SDF1) has been shown to play important roles in various processes of cardiovascular development. In recent avian studies, CXCL12 signalling has been implicated in guidance of cardiac neural crest cells for their participation in the development of outflow tract and cardiac septum. The goal of this study is to investigate the extent to which CXCL12 signalling...

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Topics

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Share to Aorta, Thoracic
Share to Chemokine CXCL12

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computed Tomography Angiography

Share to Mice, 129 Strain

Share to Neovascularization, Physiologic

Share to Pulmonary Artery

Share to Receptors, CXCR4

Share to Vascular Malformations

Source

Open in PubMed Open full text

Identifiers

PMID: 29016745
DOI: 10.1093/cvr/cvx188
PMCID: PMC6279073

Genes

CXCL12
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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