Article
The association of DNA variants at or near the IgH locus with rheumatoid arthritis.
Journal of immunogenetics - 1 Jan 2000
Sakkas L I, Demaine A G, Vaughan R W, Welsh K I, Panayi G S
Abstract excerpt
DNA samples from 78 patients with classical or definite rheumatoid arthritis (RA) and 132 healthy controls were analysed by the Southern blotting method, using two DNA probes: the first to the immunoglobulin mu heavy-chain switch region (S mu), in conjunction with the SstI restriction endonuclease, and the second to the D14S1 region, in conjunction with the HindIII restriction endonuclease. The homozygous...
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