Article
Bridging Wright-Fisher and Moran models.
Journal of theoretical biology - 21 Feb 2025
Alexandre Arthur, Abbara Alia, Fruet Cecilia, Loverdo Claude, Bitbol Anne-Florence
Abstract excerpt
The Wright-Fisher model and the Moran model are both widely used in population genetics. They describe the time evolution of the frequency of an allele in a well-mixed population with fixed size. We propose a simple and tractable model which bridges the Wright-Fisher and the Moran descriptions. We assume that a fixed fraction of the population is updated at each discrete time step. In this model, we determine the...
Read the complete abstract on PubMedTopics
- Models, Genetic
- Genetics, Population
- Population Density
- Mutation
- Selection, Genetic
- Gene Frequency
- Animals
