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Article

Exact path-integral representation of the Wright-Fisher model with mutation and selection.

BMC genomics - 12 Nov 2025

Waxman David

Abstract excerpt

The Wright-Fisher model describes a biological population containing a finite number of individuals. In this work we consider a Wright-Fisher model for an outcrossing population, where selection and mutation act at an unlinked locus. The selection acting has a general form, and the locus may have two or more alleles. We determine an exact representation of the time dependent transition probability of such a model...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41225326
DOI: 10.1186/s12864-025-12052-4
PMCID: PMC12613553

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