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Article

Inference Under a Wright-Fisher Model Using an Accurate Beta Approximation.

Genetics - 1 Nov 2015

Tataru Paula, Bataillon Thomas, Hobolth Asger

Abstract excerpt

The large amount and high quality of genomic data available today enable, in principle, accurate inference of evolutionary histories of observed populations. The Wright-Fisher model is one of the most widely used models for this purpose. It describes the stochastic behavior in time of allele frequencies and the influence of evolutionary pressures, such as mutation and selection. Despite its simple mathematical...

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PMID: 26311474
DOI: 10.1534/genetics.115.179606
PMCID: PMC4649640

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