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Article

Genetic Polymorphisms in Fatty Acid Metabolism Modify the Association Between Dietary n3: n6 Intake and Risk of Ulcerative Colitis: A Prospective Cohort Study.

Inflammatory bowel diseases - 1 Nov 2017

Ananthakrishnan Ashwin N, Khalili Hamed, Song Mingyang, Higuchi Leslie M, Lochhead Paul, Richter James M, Chan Andrew T

Abstract excerpt

INTRODUCTION: High intake of dietary n-3 polyunsaturated fatty acids (PUFA) is associated with a decreased risk of ulcerative colitis (UC) and Crohn's disease (CD). However, results have been heterogeneous suggesting that genetic variations in PUFA metabolism may modify this risk. METHODS: We conducted a case-control study nested within 2 prospective cohorts, the Nurses' Health Study (NHS) and NHS II. Among women...

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Identifiers

PMID: 28991856
DOI: 10.1097/MIB.0000000000001236
PMCID: PMC5675119

Genes

NHS
FADS1
FADS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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