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Article

Genes involved in the metabolism of poly-unsaturated fatty-acids (PUFA) and risk for Crohn's disease in children & young adults.

PloS one - 20 Dec 2010

Costea Irina, Mack David R, Israel David, Morgan Kenneth, Krupoves Alfreda, Seidman Ernest, Deslandres Colette, Lambrette Philippe, Grimard Guy, Levy Emile, Amre Devendra K

Abstract excerpt

BACKGROUND AND OBJECTIVES: Epidemiological evidence for the role of polyunsaturated fatty-acids (PUFA) in Crohn's disease (CD) is unclear, although the key metabolite leucotriene B4 (LTB(4)) is closely linked to the inflammatory process. We hypothesized that inherited variation in key PUFA metabo...

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Source

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Identifiers

PMID: 21187935
DOI: 10.1371/journal.pone.0015672
PMCID: PMC3004960

Genes

ALOX5
LTB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21187935-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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