Article
Analysis of association among clinical features and shorter leukocyte telomere length in mitochondrial diabetes with m.3243A>G mitochondrial DNA mutation.
BMC medical genetics - 8 Oct 2015
Zhou Mei-Cen, Min Rui, Ji Jian-Jun, Zhang Shi, Tong An-Li, Xu Jian-ping, Li Zeng-Yi, Zhang Hua-Bing, Li Yu-Xiu
Abstract excerpt
BACKGROUND: Mitochondrial diabetes is a kind of rare diabetes caused by monogenic mutation in mitochondria. The study aimed to summarize the clinical phenotype profiles in mitochondrial diabetes with m.3243 A>G mitochondrial DNA mutation and to investigate the mechanism in this kind of diabetes by analyzing the relationship among clinical phenotypes and peripheral leukocyte DNA telomere length. METHODS: Fifteen...
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