Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A haplotypic variant at the IRGM locus and rs11747270 are related to the susceptibility for chronic periodontitis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Feb 2018

Folwaczny Matthias, Tsekeri Eleni, Glas Jürgen

Abstract excerpt

OBJECTIVE AND DESIGN: Immunity-regulated GTPase M (IRGM) plays a critical role in the defense against intracellular bacteria by regulating autophagy formation. This direct genetic association study aimed to determine whether variants at the IRGM genetic locus are associated with chronic periodontitis. MATERIALS AND SUBJECTS: Using PCR and melting curve analysis 390 periodontitis patients and 770 healthy controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Chronic Periodontitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Germany

Share to GTP-Binding Proteins

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 28983640
DOI: 10.1007/s00011-017-1101-z

Genes

IRGM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A haplotypic variant at the IRGM locus and rs11747270 are related to the susceptibility for chronic periodontitis.PMID 28983640Read ↗

Association of autophagy-related IRGM polymorphisms with latent versus active tuberculosis infection in a Chinese population.Semantic proximity Read ↗

The Association of GLT6D1 rs1537415 G Allele with Aggressive and Advanced Chronic Periodontitis: A Comprehensive Meta-AnalysisSemantic proximity Read ↗

On the level: IRGM gene function is all about expression.Semantic proximity Read ↗

Variants in interferon gamma inducible protein 16 (IFI16) and absent in melanoma 2 (AIM2) genes that modulate inflammatory response are associated with periodontitis.Semantic proximity Read ↗

Evaluation of the Genetic Association and Methylation of Immune Response Pathway Genes with the Risk of Chronic Periodontitis in the Uighur Population.Semantic proximity Read ↗

Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis.Semantic proximity Read ↗

Association between IRGM polymorphisms and tuberculosis risk: A meta-analysis.Semantic proximity Read ↗

NLRC5 polymorphism is associated with susceptibility to chronic periodontitis.Semantic proximity Read ↗

Correlation between IRGM genetic polymorphisms and Crohn's disease risk: a meta-analysis of case-control studies.Semantic proximity Read ↗

Innate Immunity Gene Variants Affect Periodontitis Susceptibility.Semantic proximity Read ↗

A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.Semantic proximity Read ↗

The association of CSF-1 gene polymorphism with chronic periodontitis in the Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.