Article
NLRC5 polymorphism is associated with susceptibility to chronic periodontitis.
Immunobiology - 1 May 2017
Zupin Luisa, Navarra Chiara Ottavia, Robino Antonietta, Bevilacqua Lorenzo, Di Lenarda Roberto, Gasparini Paolo, Crovella Sergio
Abstract excerpt
Periodontitis is a chronic oral pathology caused by impaired immune response against oral bacteria resulting in tissue inflammation and damage. Among the members of innate immune response, the first line of defence against pathogens, inflammasomes are macro-molecular protein complexes that can be activated by different stimuli, comprised bacteria infections. Different proteins are involved in inflammasoma...
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