Article
Variants in interferon gamma inducible protein 16 (IFI16) and absent in melanoma 2 (AIM2) genes that modulate inflammatory response are associated with periodontitis.
Archives of oral biology - 1 Mar 2023
Barrientos Marcia Otto, Cruz Álvaro A, Teixeira Helena M P, Silva Hátilla Dos Santos, Gomes-Filho Isaac Suzart, Trindade Soraya Castro, Soledade Kaliane Rocha, Fernandes Jamille Souza, Santana Cinthia Vila Nova, Pinheiro Gabriela Pimentel, Souza-Machado Adelmir, Costa Ryan Dos Santos, Figueiredo Camila A, Oliveira Tatiane Teixeira Muniz Carletto
Abstract excerpt
OBJECTIVE: Evaluate the association of genetic variants of the interferon gamma inducible protein 16 (IFI16) and absent in melanoma 2 (AIM2) genes with periodontitis. METHODS: The study involved 117 individuals with periodontitis and 389 without periodontitis, all Brazilians, miscegenated. Individuals with periodontitis presented at least 4 teeth with ≥ 1 site with probing depth ≥ 4 mm; clinical attachment level...
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