A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.

doi:10.1093/hmg/ddp508

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A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.

Human molecular genetics - 1 Feb 2010

Schaefer Arne S, Richter Gesa M, Nothnagel Michael, Manke Thomas, Dommisch Henrik, Jacobs Gunnar, Arlt Alexander, Rosenstiel Philip, Noack Barbara, Groessner-Schreiber Birte, Jepsen Søren, Loos Bruno G, Schreiber Stefan

Abstract excerpt

Periodontitis is a widespread, complex inflammatory disease of the mouth, which results in a loss of gingival tissue and alveolar bone, with aggressive periodontitis (AgP) as its most severe form. To identify genetic risk factors for periodontitis, we conducted a genome-wide association study in German AgP patients. We found AgP to be strongly associated with the intronic SNP rs1537415, which is located in the...

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PMID: 19897590
DOI: 10.1093/hmg/ddp508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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