Article
Peripheral Tr1 and Foxp3+ Treg as Markers of Recurrent Malignancies in Patients with Hepato-Biliary Pancreatic Cancers.
Anticancer research - 1 Oct 2017
Ikemoto Tetsuya, Shimada Mitsuo, Ishikawa Daichi, Kawashita Yoichiro, Teraoku Hiroki, Yoshikawa Masato, Yamada Shinichiro, Saito Y U, Morine Yuji, Imura Satoru
Abstract excerpt
BACKGROUND/AIM: Recently CD4+CD49b+ LAG3+regulatory T (Tr1) cells are reported to be IL-10 driven, have strong regulatory activities. Thus, this study aimed to investigate whether Treg and Tr1 cells participate in immunological status against cancer. PATIENTS AND METHODS: Peripheral blood was withdrawn from patients (n=78), and healthy volunteers as controls (n=23). The peripheral blood mononuclear cells were...
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