Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Causes of Functional Adrenocortical Adenomas.

Endocrine reviews - 1 Dec 2017

Zennaro Maria-Christina, Boulkroun Sheerazed, Fernandes-Rosa Fabio

Abstract excerpt

Aldosterone and cortisol, the main mineralocorticoid and glucocorticoid hormones in humans, are produced in the adrenal cortex, which is composed of three concentric zones with specific functional characteristics. Adrenocortical adenomas (ACAs) can lead to the autonomous secretion of aldosterone responsible for primary aldosteronism, the most frequent form of secondary arterial hypertension. In the case of...

Topics

Join the communities discussing this publication.

Adrenal Cortex Neoplasms
Adrenocortical Adenoma
Cushing Syndrome
Genetic Predisposition to Disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28973103
DOI: 10.1210/er.2017-00189

Genes

PRKACA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Causes of Functional Adrenocortical Adenomas.PMID 28973103Read ↗

Genetics of Primary Aldosteronism.Semantic proximity Read ↗

Molecular Genetic and Genomic Alterations in Cushing’s Syndrome and Primary AldosteronismSemantic proximity Read ↗

Genetic Alterations in Benign Adrenal TumorsSemantic proximity Read ↗

Adrenocortical tumorigenesis: Lessons from genetics.Semantic proximity Read ↗

Molecular Basis of Primary Aldosteronism and Adrenal Cushing SyndromeSemantic proximity Read ↗

Genetic causes of primary aldosteronismSemantic proximity Read ↗

Genetic Landscape of Sporadic Unilateral Adrenocortical Adenomas Without PRKACA p.Leu206Arg Mutation.Semantic proximity Read ↗

Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas.Semantic proximity Read ↗

GENETICS IN ENDOCRINOLOGY: The expanding genetic horizon of primary aldosteronism.Semantic proximity Read ↗

Genetics of adrenocortical tumoursSemantic proximity Read ↗

PRKACA Somatic Mutations Are Rare Findings in Aldosterone-Producing AdenomasSemantic proximity Read ↗

A genetic and molecular update on adrenocortical causes of Cushing syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.