Article
Chymotrypsinogen C Genetic Variants, Including c.180TT, Are Strongly Associated With Chronic Pancreatitis in Pediatric Patients.
Journal of pediatric gastroenterology and nutrition - 1 Dec 2017
Grabarczyk Alicja Monika, Oracz Grzegorz, Wertheim-Tysarowska Katarzyna, Kujko Aleksandra Anna, Wejnarska Karolina, Kolodziejczyk Elwira, Bal Jerzy, Koziel Dorota, Kowalik Artur, Gluszek Stanislaw, Rygiel Agnieszka Magdalena
Abstract excerpt
OBJECTIVES: Genetic studies in adults/adolescent patients with chronic pancreatitis (CP) identified chymotrypsinogen C (CTRC) genetic variants but their association with CP risk has been difficult to replicate. To evaluate the risk of CP associated with CTRC variants in CP pediatric patients-control study. METHODS: The distribution of CTRC variants in CP pediatric cohort (n = 136, median age at CP onset 8 years)...
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