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Article

Chymotrypsin C mutations in chronic pancreatitis.

Journal of gastroenterology and hepatology - 1 Aug 2011

Zhou Jiayi, Sahin-Tóth Miklós

Abstract excerpt

Chronic pancreatitis is a persistent inflammatory disorder characterized by destruction of the pancreatic parenchyma, maldigestion, and chronic pain. Mutations in the chymotrypsin C (CTRC) gene encoding the digestive enzyme CTRC have been shown to increase the risk of chronic pancreatitis in European and Asian populations. Here, we review the biochemical properties and physiological functions of human CTRC,...

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Source

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Identifiers

PMID: 21631589
DOI: 10.1111/j.1440-1746.2011.06791.x
PMCID: PMC3142265

Genes

CTRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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