Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple Gene-Environment Interactions on the Angiogenesis Gene-Pathway Impact Rectal Cancer Risk and Survival.

International journal of environmental research and public health - 28 Sept 2017

Sharafeldin Noha, Slattery Martha L, Liu Qi, Franco-Villalobos Conrado, Caan Bette J, Potter John D, Yasui Yutaka

Abstract excerpt

Characterization of gene-environment interactions (GEIs) in cancer is limited. We aimed at identifying GEIs in rectal cancer focusing on a relevant biologic process involving the angiogenesis pathway and relevant environmental exposures: cigarette smoking, alcohol consumption, and animal protein intake. We analyzed data from 747 rectal cancer cases and 956 controls from the Diet, Activity and Lifestyle as a Risk...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Diet

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Life Style

Share to Logistic Models

Share to Neovascularization, Pathologic

Share to Proportional Hazards Models

Share to Rectal Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 28956832
DOI: 10.3390/ijerph14101146
PMCID: PMC5664647

Genes

EGR2
TLR4
CXCR1
EGFR
KDR
MMP1
PDGFB
TLR2
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple Gene-Environment Interactions on the Angiogenesis Gene-Pathway Impact Rectal Cancer Risk and Survival.PMID 28956832Read ↗

A Candidate-Pathway Approach to Identify Gene-Environment Interactions: Analyses of Colon Cancer Risk and Survival.Semantic proximity Read ↗

Interactions between environmental factors and polymorphisms in angiogenesis pathway genes in esophageal adenocarcinoma risk: a case-only study.Semantic proximity Read ↗

Integrative network modeling of colorectal cancer reveals diagnostic signatures and therapeutic targetsSemantic proximity Read ↗

Review of the Gene-Environment Interaction Literature in Cancer: What Do We Know?Semantic proximity Read ↗

Impact of Gene-Environment Interactions on Cancer Development.Semantic proximity Read ↗

Using gene-environment interactions to explore pathways for colorectal cancer risk.Semantic proximity Read ↗

Biomarker Prediction and Immune Landscape of Angiogenesis in Inflammatory Bowel Disease: Insights from Bioinformatics and Machine Learning ApproachesSemantic proximity Read ↗

Oesophageal squamous cell carcinoma in high-risk Chinese populations: Possible role for vascular epithelial growth factor A.Semantic proximity Read ↗

Gene-gene interactions in gastrointestinal cancer susceptibility.Semantic proximity Read ↗

VEGFA, FLT1, KDR and colorectal cancer: assessment of disease risk, tumor molecular phenotype, and survival.Semantic proximity Read ↗

Polymorphisms in the Angiogenesis-Related Genes EFNB2, MMP2 and JAG1 Are Associated with Survival of Colorectal Cancer Patients.Semantic proximity Read ↗

SNP-SNP interaction network in angiogenesis genes associated with prostate cancer aggressiveness.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.