Article
SNP-SNP interaction network in angiogenesis genes associated with prostate cancer aggressiveness.
PloS one - 1 Jan 2013
Lin Hui-Yi, Amankwah Ernest K, Tseng Tung-Sung, Qu Xiaotao, Chen Dung-Tsa, Park Jong Y
Abstract excerpt
Angiogenesis has been shown to be associated with prostate cancer development. The majority of prostate cancer studies focused on individual single nucleotide polymorphisms (SNPs) while SNP-SNP interactions are suggested having a great impact on unveiling the underlying mechanism of complex disease. Using 1,151 prostate cancer patients in the Cancer Genetic Markers of Susceptibility (CGEMS) dataset, 2,651 SNPs in...
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