Article
Targeting Innate Immunity for Type 1 Diabetes Prevention.
Current diabetes reports - 27 Sept 2017
Needell James C, Zipris Danny
Abstract excerpt
PURPOSE OF REVIEW: Despite immense research efforts, type 1 diabetes (T1D) remains an autoimmune disease without a known trigger or approved intervention. Over the last three decades, studies have primarily focused on delineating the role of the adaptive immune system in the mechanism of T1D. The discovery of Toll-like receptors in the 1990s has advanced the knowledge on the role of the innate immune system in...
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