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Article

The prognostic impact of mutations in spliceosomal genes for myelodysplastic syndrome patients without ring sideroblasts.

BMC cancer - 27 Jun 2015

Kang Min-Gu, Kim Hye-Ran, Seo Bo-Young, Lee Jun Hyung, Choi Seok-Yong, Kim Soo-Hyun, Shin Jong-Hee, Suh Soon-Pal, Ahn Jae-Sook, Shin Myung-Geun

Abstract excerpt

BACKGROUND: Mutations in genes that are part of the splicing machinery for myelodysplastic syndromes (MDS), including MDS without ring sideroblasts (RS), have been widely investigated. The effects of these mutations on clinical outcomes have been diverse and contrasting. METHODS: We examined a cohort of 129 de novo MDS patients, who did not harbor RS, for mutations affecting three spliceosomal genes (SF3B1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26115659
DOI: 10.1186/s12885-015-1493-5
PMCID: PMC4483202

Genes

SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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