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PRAME Gene Copy Number Variation Is Related to Its Expression in Multiple Myeloma

27 Sept 2017

Abstract excerpt

Multiple myeloma (MM) patients commonly present abnormal expression of cancer-testis antigens, which may serve as immunotherapeutic targets and prognostic factors. We previously reported that preferentially expressed antigen of melanoma (PRAME) overexpression in bone marrow mononuclear cells is related to progression in MM patients treated with non-bortezomib-containing regimens. The mechanism underlying...

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PMID: 28953414
DOI: 10.1089/dna.2017.3951

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