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Article

Evaluation of sFLT1 protein levels in human eyes with the FLT1 rs9943922 polymorphism.

Ophthalmic genetics - 1 Jan 2000

Chirco Kathleen R, Lewis Carly J, Scheetz Todd E, Johnston Rebecca M, Tucker Budd A, Stone Edwin M, Fingert John H, Mullins Robert F

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD) is a devastating disease characterized by central vision impairment in individuals with advanced age. Neovascular AMD is a form of end-stage disease in which choroidal vessel outgrowth occurs beneath the retina. While many hypotheses have been raised as to what triggers the formation of pathological choroidal neovascular membranes, the exact mechanism for their...

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Source

Open in PubMed Open full text

Identifiers

PMID: 28949775
DOI: 10.1080/13816810.2017.1369550
PMCID: PMC5751420

Genes

FLT1
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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